Melanotan 2 (MT-II) is supplied in a generous 10mg / 3ml pre-filled research pen – the classic cyclic heptapeptide analog of α-MSH (alpha-melanocyte-stimulating hormone), widely utilized in laboratory studies of melanocortin receptor pharmacology, pigmentation pathways, photoprotection mechanisms, and central melanocortin-mediated behaviors.

Melanotan 2 is a potent, non-selective agonist of the melanocortin receptors (primarily MC1R, MC3R, MC4R, and MC5R), with structural modifications (including D-Phe at position 7 and lactam cyclization between Asp5-Lys10) that confer dramatically increased potency, stability, and resistance to enzymatic degradation compared to native α-MSH.

Key areas of research investigation include:

• Robust stimulation of eumelanin synthesis and skin darkening (tanning) via MC1R activation in melanocytes
• Photoprotective effects: increased melanin production as a natural UV shield, potential reduction in UV-induced DNA damage
• Exploration of appetite suppression and body weight regulation through central MC4R signaling
• Modulation of sexual arousal, erectile function, and libido-related pathways (via MC3R/MC4R in the CNS)
• Investigation of anti-inflammatory, immunomodulatory, and cardiovascular effects linked to melanocortin system activation
• Studies on pain modulation, neuroprotection, and behavioral responses mediated by melanocortin receptors

The 10mg strength in a 3ml pen offers excellent dosing flexibility for both short- and longer-term experimental protocols, with Melanotan 2’s extended biological activity (half-life ~1–2 hours, but cumulative receptor effects lasting days) supporting infrequent administration schedules in many research models.

Product highlights:

• Ultra-high purity Melanotan 2 Acetate (>99% – third-party HPLC & MS verified)
• Sterile, ready-to-use pre-filled pen injector – precise, convenient, and optimized for laboratory use
• Stable cyclic structure for reliable and reproducible melanocortin receptor activation