NAD+ is supplied in a high-concentration 600mg / 3ml pre-filled research pen – the cornerstone coenzyme used in advanced laboratory studies of cellular energy metabolism, redox homeostasis, sirtuin activation, DNA repair, mitochondrial function, and age-related biological pathways.

Nicotinamide Adenine Dinucleotide (NAD+) is a critical pyridine nucleotide coenzyme found in all living cells. It serves as an essential cofactor in hundreds of redox reactions (facilitating electron transfer in glycolysis, TCA cycle, and oxidative phosphorylation) while acting as the primary substrate for key regulatory enzymes including:

• Sirtuins (SIRT1–7) – NAD+-dependent deacetylases regulating gene expression, metabolism, stress resistance, and longevity pathways
• PARPs (Poly-ADP-ribose polymerases) – DNA damage sensing and repair
• CD38/CD157 – NAD+ consumption and calcium signaling

Exogenous NAD+ research focuses on elevating intracellular and extracellular NAD+ pools to investigate restoration of age-, stress-, or disease-associated declines.

Major research domains include:

• Enhancement of mitochondrial biogenesis, ATP production, and oxidative phosphorylation efficiency
• Activation of sirtuin pathways and downstream effects on metabolic health, insulin sensitivity, and inflammation control
• Investigation of DNA repair capacity, genomic stability, and cellular senescence modulation
• Studies on neuroprotection, cognitive function, and neurodegeneration models (Parkinson’s, Alzheimer’s, etc.)
• Exploration of cardiovascular protection, vascular endothelial function, and metabolic syndrome reversal
• Anti-aging and longevity research: NAD+ as a pivotal link between caloric restriction, exercise, and lifespan extension mechanisms
• Muscle function, exercise performance/recovery, and sarcopenia prevention models

The 600mg strength in a 3ml pen provides substantial capacity for higher-dose protocols, extended administration studies, or experiments requiring robust NAD+ elevation, with direct delivery formats allowing investigation of bioavailability and tissue distribution in various models.

Product highlights:

• Ultra-high purity NAD+ (>99% – third-party HPLC & MS verified)
• Sterile, ready-to-use pre-filled pen injector – precise dosing and maximum laboratory convenience
• Stabilized formulation optimized for research-grade NAD+ stability